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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'df6c4ad2fd91a94ee3fd0fbde9a52d242f494a3ee71395f85c794249871c4bc0' 
  AND token = '3+2Xh4CS/l02Y0j1CTOxTKKRkOGjPvgUFHOf0yk1c1E=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}