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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4e808258b66bb0d359dd3a2cd804def8617cfa8b30b2a61015bcda7cba95785a' 
  AND token = 'Z2jIOQbDCZOTAJLqoWPB38FFXBAPTU6gngWt4yhkd5M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}