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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '54e45f48fa79170f10292de71a395d160be1e80d0f92a42ee3e4632632c4a837' 
  AND token = '7ukYmF5FLiUn+6NFrReIOZd+IjThIa+xmcV4IoKXNqg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}