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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '265c53c13de3c1e71a81b0fc41f887689c472fdb2efb7cb2100adfa335118bd5' 
  AND token = 'GhIpeIe/AHVHtSt3bvduU/t3PrF8P8SRFg61i+w0GS4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}