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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81be1e24208521d3ffb2fc16d2b44f5daf454a102b66aa1be54f6f908c955f6a' 
  AND token = 'MT0Hb5PXUqcFphrfhVi6riXau7E0E5HbPMpG7CksI3Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}