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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5471036323ec594dfd002d04248295117b5451506b617ebf9058f117c295a7f4' 
  AND token = 'QwmoCrUhDxi3ezS0sIIcx0PBefXOIIy0x70SsLaFrX4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00024

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}