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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e0d313706a6787cb8a7dc363ca5190229206857ebdb4004d5729e1777d8f9174' 
  AND token = 'PilHCZZBz6IGBtVoe+KKJR0dF7x83I9oTNBBT5EWjik=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}