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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c39824d0f716e1b2bf8e6e0f4ccc1e5a41551f36341613aac22d71614a67a402' 
  AND token = 'H7PxNZwepGu2g8Lp0vY0+LQSXg+iEJgtdiojSyUe93A=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}