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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '00dc41c75b342eac83919e921a2a4727abd78f358cb253ccd63168139b192496' 
  AND token = 'P9C2hr7Yq/9EhocA5v4Rz6ehS6IPdp1eL3V2+DMAdho=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}