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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f25930babe2a000faf7c06ff3329c926d9b881e69c352174f5a32d051868d513' 
  AND token = '8j+8wN1ZmxMfnbeT79ukvJV8MtvrM5hatA1fmMDhwSE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00020

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}