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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1fc01540879d158f2688ff8f50d3e29a9799c07886a69c8b6b788c03dc99b345' 
  AND token = 'exM0lRDyJKQpGxQVwQtIO4+pgIkoIqS9du11StZtwSQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00039

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}