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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '49f3ac476b742ea72b8c5424b327201e256377bb46c12149b962813c1d18306e' 
  AND token = 'K4hr9F3cOcIKYgLBqD+AnS4DngX9cIxFLzAWqAKbrc8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00044

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}