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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a787db075123603e853de87f187b005e1040d2dff22e1d65b397d0498d80b548' 
  AND token = 'GCODtiglCHT7OrMszVHwFZYhtDdozSMXbiRX37RTLSA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}