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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '0f0ed33b20f81d60287ba1e2ed04b51d27b4ca863840e87ae9999300be316d1f' 
  AND token = 'y/4/t8fDHUhCVcdQQMnRTPgfk3wcKa/O0umYkyQd0gI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}