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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ff123b69bc12976ac5fe64b934e2fb60fd81a991ef9bf01d130d79a0503260d4' 
  AND token = '4aXyrNO6av0eprExD1arDCkiUxjTMnYv7v1/23kz66s=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00095

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}