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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '8811269a6a2da489505436b7de2543cce5df89a0798a1d9f49cecfab0c2cf829' 
  AND token = '42ma4ZEiQ8vtj65Nd04IaZ/F5LKOqTi0t8g+m0ZnkZ8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}