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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '22b1e30168781205253ceb902ca7c4cc09954d6ad872c57054cd34362c657071' 
  AND token = 'NL7tibdVYQ0oRZyqsFPQN5fb1zYSMUbbVYqh+gA6uzk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00036

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}