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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '82ec72ea752e5c4497ddc487dceca551d8834cf02b96295f37e03b54826ad8d3' 
  AND token = 'MKi2WBT1g4Y4DT0PM6zyiNoMwETiysa6jiGhquxqmNw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}