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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b7b7851f5c67579d1bb9ef75e3c3b92128d8bd567c590c06fcb64e3125293fc8' 
  AND token = 'TytkQYWZZCiOCDcdQ8PtRA9AbQQkUk6GevTfn8h9ZhA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00032

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}