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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3613eeb22a036a3c77ffe32de0254ba597f577ad0521f4236edb2acfb6ea933b' 
  AND token = '/mrPYOf+iQHOvYPrLqkZQn1CqtEW7XUs9f1ed/tqLhI=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}