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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '32b1a12b8f584ade7337a09f5c0983ada2281de5fac26bf8b8c60c1f521faac1' 
  AND token = 'igLk2Tc02/krd2chNi4wiyijEh8Pw/kKqXQQL0XBPS0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00054

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}