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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '38f0c848a4c87cb5f822ad4847b60a7d2eedf44e307aa25c39496e3113aec955' 
  AND token = '7Etfvb9c59rabkI9draD796qmTbanXhfxKnIlYz+qJw=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00049

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}