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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1ed8b8e943cb7989c5fbf307fc0f0c48ee907573f667c1eef70fc5d22702552b' 
  AND token = 'ZNUdfLdafHhSbvy+KVbkMj9vkR+PzqWUOgG5hLLCl5o=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}