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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5c8f38a3a20b093288d133371bed4a5a8bb67d390edd4390f16f41df402d5d67' 
  AND token = 'PrKAD+RdxGjDpAX/fBFMU3p9h0qqqjQ8CQIueekk00Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00037

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}