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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '465a309fc97df71823f9ece6d1fba40b0778eb9602bbb152182cdb3d6af0fd17' 
  AND token = '2tK9/NqwSQe6pSYNGF0IaFhX+UfEseyd6g273/PBHNQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}