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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f287293ee3b4551e8f97b36ef50c1f1138f7b392adac100969cde16f18444915' 
  AND token = 'AdokrBvw9jokKrfcKuo7GwsHYs0WSN+IwIiTKd+cIKE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}