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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '052268ca8a334884ddb9abc47e4ae3673e6b88b32f6c2626ee44d9c5f494648c' 
  AND token = 'omC9eP8keDLPXdKMQbEPiXgD+OzSuuneuXaYlnpXLH0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}