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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '5a5eb0d40eec8f9910015fb07c3557ae366875eec3708da35c05d1888b689a5f' 
  AND token = '2544vceMecpNJQweLzyL2KeqGtp8QGYOSWomnsdHhbE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00048

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}