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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '1cdb8535417326198c091f071c559e870378e5b21ee37445895e26bac917c18c' 
  AND token = 'iM8Kat9ToY4VD3RkBMl/2CYezj42V6jI9wLOQZ7/PQ4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00033

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}