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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b40dc35ad1597a3755926becae3109b8d9dae944a428c8b4dbee99a0a7d44377' 
  AND token = 'akk+nqlCoUe/APvatRbsrYb6aAhNdYy3a9TMPzqwErU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00026

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}