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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'f1b744c6c63f9689e82efdf1af40c6e1b340344a47f8f059c87ab9f246352b2a' 
  AND token = 'ox+KdHe2aDsy7SjP2DM4/1wPZ9Sm1Ps356RtBzEvGYs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00025

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}