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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '3ec0498b6da8aa50ffe7c6e3312301f04f48e8eb56711289148d86161261696f' 
  AND token = 'nw2HC9kBct5Vjy0GluRJGFCV2rLA+N2V6SJwO6EXLXo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00057

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}