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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '4aaddc8a8fbab14c1c8f44d9adf852197b41221f3c59a8544745055505af8e1f' 
  AND token = 'kXC1xToxEhPpd+gU6aQCvJxL/LvWiBBq1eYXlhUBmBg=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}