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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ac5f8c1015ab3ce636dff02a486143347786fadd3a31f13b851b2755f54d023e' 
  AND token = 'ut7u7/14HmTZbVvz0Zmn+ldyJQuKKT4JJpOR12tY/rk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00021

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}