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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '53f4303c232db0a6bc0618a9c720675a2db0d3663956399cf84fb5d57703bb61' 
  AND token = 'PojB4k/RFvu8dwpX57y8CCrDJvGywPY059M2aK/KbBE=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00069

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}