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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '9944a6b3a290b57fc411bf377f28ef28bd31ff0ba5e2642a74a36b8e68799d00' 
  AND token = 'Z6ukTkOM9DQXBl/GqLP+fsQmmiIat5DyXfLOi6O6jC8=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00043

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}