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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a4e34e0d665b08eaed0e43891cfb64538596aedd8e43490f3bb698514ce22d33' 
  AND token = 'tpjj0H0oR32v9FBim+7ijpTGFek64etQmGAZDk/f0K4=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}