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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'a8c8d4d283eb210f33efdab7151b7b3188c2dff4acb35f80efc91b7c62731915' 
  AND token = 'c7WTNrQDybewHy4uwMHBWg2NTmqB5DFkGO+lg6js5cQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00029

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}