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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b1d1993bf4706505b2208517f017ddaaf6470e2e3c8af79a38186c94cd2f67e1' 
  AND token = 'zsnAR1G+GtiwcPoO2sWR9EAWHAF6bYKbS0g2Y4Z0gEA=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00041

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}