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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '44326b051604bf399051ad871d1f4c83006e8a14feac368dfecc7c88799b56af' 
  AND token = 'CGAgphpE270Jru4M/zMJauk677X8QugqY85E/OLzLdc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00061

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}