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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '01b5debd0deafa8c06029c1d16cc22dd56bd534322e44dafb4db8e2ad28eb825' 
  AND token = '/NAAENcaDM2qL9kH/nAy6aMp/DfFUx0K+M0CUN9M6g0=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00055

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}