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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'c7e3e143c6987ffe30e42af4e10c80e795e7594dfb2b46e82f7fea174241d2f9' 
  AND token = 'J2yh+//L7qtfeJ+vmuTuBQm1CSh7UOIwP3AKzUfETEo=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00046

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}