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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'b39d9e898c615541310d6033f7143e5a6dd7b97a7815027255c490e6bd11e0dc' 
  AND token = 'l0W5nI6P0u984vAnab+251QvEK9re09fZ6PItm7myKs=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00047

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}