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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e39cc5a378bd7df21aae39e93b940a2d56e91ca06e63f11fb3a8e938981c2acf' 
  AND token = 'JuFI9yTTS4K5n6BQxiIgbS5U+H3kIDMTP81tHvReHFM=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00052

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}