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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '6b427184e96bdc32131e9ad44f19164cd6c220a82a1f1cf277244ae04ab3a2a1' 
  AND token = '+1cP3ijYqK4qlay/GxtZxmNvP70LWfAVMqeJ+7mt6Fk=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00064

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}