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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '85cae5dd38178e220a918c41fba04d9e75a626f57605aeb16c90fb5cae80a160' 
  AND token = 'N4DzYXDt2oHiI5MpDb3rzWtd6nkBmKzxX2en9UUHnwQ=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00034

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}