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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '81c3dca58bddddf4ca220e440a32c28671a4e93bbd243ab34ff08fa231eaa442' 
  AND token = 'Uu35kBGjsZ8ko9HFwBYEhjGEdJh7O849wGe3nfE+e4Q=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}