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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = '2c57264c1268b63cde6953637064bf1e6f23982b6fa29cd0175e5049c9365e3a' 
  AND token = '//kKTA+QSDXXsqeH5VF18jwnwSzaXrJdzrewhS/eSbc=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00027

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}