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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'ae4858a335d78a756e09104b5947e5d0d84c0428bbb31ab8d1a8a822e73f2662' 
  AND token = 'WhxrKVDaxeiHMjUjV7G1PmEllW+Nqmxo1Ix0pLPZ5tU=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00042

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}