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SELECT 
  1 
FROM 
  cscart_lock_keys 
WHERE 
  key_id = 'e78bd9f0d01266b701a0ff0c98739d08d69171360a944638a58b3054e6aeb8b1' 
  AND token = 'sge4ASrHdxudQ+UPlSDabvF+XZyEZGb+sXzTrpC85/M=' 
  AND expiry_at > UNIX_TIMESTAMP(NOW())

Query time 0.00045

JSON explain

{
  "query_block": {
    "select_id": 1,
    "message": "no matching row in const table"
  }
}